James R. Downing, M.D., president and CEO of St. Jude Children's Research Hospital, is the No. 5 ranked CEO in the large company category of Glassdoor's Top CEOs. Glassdoor is a website where employees and former employees anonymously review companies and their management. Winning CEOs are determined by feedback from their employees who review their performance on Glassdoor.com.

Under Downing's leadership, St. Jude has increased employee feedback channels and forums, resulting in more innovation and connectivity across the Memphis-based campus. Downing leads monthly Town Hall and Blueprint Series all-employee meeting opportunities that encourage employees to share ideas and connect with leadership.